Florida State vs. Duke prediction, odds, spread: 2024 college football picks, prop bets from proven expert

The Florida State Seminoles (1-5, 1-4) aim to turn their season around when they travel to Durham, N.C. to take on the Duke Blue Devils (5-1, 1-1) in a primetime ACC matchup on Friday. The Noles entered the season with high expectations after going 13-1 in 2023. FSU is coming off a bye week, and will be looking to bounce back from a 29-13 blowout loss to Clemson. Duke will be looking to clinch bowl eligibility and notch its first ever win against Florida State. The Blue Devils are also coming off a bye, and are looking to rebound from their 24-14 loss to Georgia Tech on Oct. 5. 

Kickoff is scheduled for 7 p.m. ET. The Blue Devils are favored by 3 points in the latest Duke vs. Florida State odds via SportsLine consensus, while the over/under is 42.5 points. Before making any Florida State vs. Duke picks, you need to see the Week 8 college football predictions and betting advice from SportsLine’s Jimmie Kaylor. 

Kaylor is an NFL, college football and DFS expert for SportsLine, who has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America. His background as a former college football All-American and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks. He has his finger on the pulse of the college football landscape and has been cashing in big on sports betting apps for the last two years. 

Kaylor has destroyed the sportsbooks in college football the last two seasons, netting a whopping 53.9 units while posting a 163-102-2 record since Week 1 of the 2023 season. Anyone who followed his picks finished the season way up.

Now, Kaylor has dialed in on Duke vs. FSU on Friday and just revealed his college football picks and predictions. You can head to SportsLine now to see his picks. Here are the college football odds and betting lines for FSU vs. Duke:

• Florida State vs. Duke spread: Duke -3
• Florida State vs. Duke over/under: 42 points
• Florida State vs. Duke money line: Duke -146, Florida State +121
• Florida State vs. Duke picks: See picks at SportsLine
• Florida State vs. Duke streaming: FuboTV (Try for free)

Why Duke can cover

Duke is 2-1-2 against the spread this season. Texas transfer Maalik Murphy has settled in nicely as the Blue Devils starting quarterback. The 6-foot-5 sophomore has thrown for 1,431 yards, 14 touchdowns and five interceptions. Running back Star Thomas, a transfer from New Mexico State, has paced the rushing attack. Through five games, he’s rushed for 528 yards and three touchdowns on 113 carries. 

Defensively, the Blue Devils rank near the top of the ACC. The Blue Devils rank second in the conference in both total yards allowed per game (309.3) and points allowed per game (17.5). Linebacker Alex Howard leads the team with 47 total tackles and has also tallied 3.0 sacks. See which team to pick here. 

Why Florida State can cover

The Seminoles will once again be without veteran quarterback DJ Uiagalelei, who remains sidelined with a hand injury. Freshman Brock Glenn will start in his place for the second consecutive game. In his first start against Clemson, Glenn completed 23 of 41 passes for 228 yards, two touchdowns and one interception.

Defensively, the Noles have multiple players who will go on to be NFL Draft picks. The Florida State pass rush is among the best in the ACC, with four players each having 2.5 or more sacks for the season. Junior Patrick Payton leads the way with 4.0 sacks. See which team to pick here. 

How to make Duke vs. Florida State picks

Kaylor has analyzed Florida State vs. Duke from every angle and he’s leaning Over on the point total. He has also discovered a critical X-factor that has him jumping all over one side of the spread. He’s only sharing what it is, and which side to back, at SportsLine.

So who wins Duke vs. Florida State on Friday, and what critical X-factor makes one side of the spread a must back? Visit SportsLine now to see which side of the spread to jump on, all from the expert who has profited $5,390 for $100 college football bettors since Week 1 of 2023 season, and find out.