Cowboys vs. Saints odds, picks, line, time: 2024 NFL picks, Week 2 predictions from advanced computer model

The Dallas Cowboys (1-0) will try to extend their impressive 16-game home regular-season winning streak when they host the New Orleans Saints (1-0) on Sunday afternoon. Dallas lost to Green Bay at home in the wild-card round last year, but it has been untouchable at home during the regular season. The Cowboys are coming off a 33-17 win over the Browns in Week 1, while the Saints had the highest point total of any team last week when they cruised to a 47-10 win over the Panthers. This is the first meeting between these teams since 2021, when the Cowboys notched a 27-17 road win.

Kickoff is scheduled for 1 p.m. ET on Sunday at AT&T Stadium in Arlington, Texas. Dallas is a 6.5-point favorite in the latest Cowboys vs. Saints odds from SportsLine consensus, while the over/under for total points is 47. Before entering any Saints vs. Cowboys picks, you’ll want to see the NFL predictions from the model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 2 of the 2024 NFL season on an incredible 184-130 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 38-22 roll on top-rated NFL picks since Week 7 of 2022. 

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

The model has set its sights on Dallas vs. New Orleans. You can head to SportsLine to see its picks. Here are several NFL betting lines for the spread, money line and over/under:

• Cowboys vs. Saints spread: Cowboys -6.5
• Cowboys vs. Saints over/under: 47 points
• Cowboys vs. Saints money line: Cowboys -280, Saints +228
• Cowboys vs. Saints picks: See picks at SportsLine

Why the Cowboys can cover

Dallas posted a perfect 8-0 record at home last season, covering the spread in six of those games. The Cowboys are also 6-1 in their last seven home openers, and they are coming off a 33-17 win at Cleveland as 1.5-point road underdogs. Quarterback Dak Prescott threw for 179 yards and a touchdown, while six players combined for 103 rushing yards.

The Cowboys were even better defensively, forcing two turnovers and holding Browns quarterback Deshaun Watson to a 24 of 45 mark. Saints quarterback Derek Carr is facing a star-studded Dallas linebacker group, headlined by Micah Parsons. New Orleans is coming off a strong performance against Carolina, but the Panthers are one of the worst teams in the league and the Saints have only covered the spread once in their last seven September games. See which team to pick here.

Why the Saints can cover

New Orleans put on a clinic in its first game with new offensive coordinator Klint Kubiak, setting franchise records for points in an opener (47) and consecutive scoring drives to start the season (9). Veteran quarterback Carr completed 19 of 23 passes for 200 yards and three touchdowns, connecting with wide receiver Rashid Shaheed three times for 73 yards. 

The Saints also racked up 180 rushing yards on 37 carries, averaging 4.9 yards per attempt. Running back Alvin Kamara finished with 110 total yards and a touchdown. New Orleans has covered the spread in five of its last six games, while Dallas has only covered twice in its last six games. See which team to pick here. 

How to make Cowboys vs. Saints picks

The model has simulated Saints vs. Cowboys 10,000 times and the results are in. The model is leaning Over, and it also says one side of the spread is the better value. You can only see the pick at SportsLine.

So who wins Dallas vs. New Orleans on Sunday, and which side of the spread is the better value? Visit SportsLine right now to see which side of the Saints vs. Cowboys spread you should be all over Sunday, all from the model on a 184-130 roll on its top-rated NFL picks, and find out.