Texas A&M vs. Missouri odds, spread, line: 2024 college football picks, Week 6 predictions from proven model

The No. 9 Missouri Tigers (4-0) will return from their bye week when they travel to face the No. 25 Texas A&M Aggies (4-1) on Saturday afternoon in the only matchup of ranked teams on the Week 6 college football schedule. Missouri opened the season with a perfect four-game homestand, wrapping it up with a double-overtime win over Vanderbilt two weeks ago. Texas A&M has another chance to take down a top-10 team at home, as it fell to then-No. 7 Notre Dame in its season opener. Texas A&M quarterback Conner Weigman, who has missed the past three games with a shoulder injury, is listed as questionable. Missouri receiver Marquis Johnson (ankle) is out. 

Kickoff is set for noon ET on Saturday at Kyle Field. After opening at -2. the Aggies are now favored by 2.5 points in the latest Texas A&M vs. Missouri odds, while the over/under is 47.5 points, per SportsLine consensus. Before entering any Missouri vs. Texas A&M picks, you’ll want to see the college football predictions from the model at SportsLine.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of well over $2,000 for $100 players on its top-rated college football picks against the spread. It also went a sizzling 6-0 on all top-rated college football picks in Week 5. Anyone who has followed it has seen strong returns.

The model has set its sights on Missouri vs. Texas A&M. You can head to SportsLine to see its picks. Here are several college football betting lines for the spread, money line and over/under on this game:

• Texas A&M vs. Missouri spread: Texas A&M -2.5
• Texas A&M vs. Missouri over/under: 47.5 points
• Texas A&M vs. Missouri money line: Texas A&M -140, Missouri +117
• Texas A&M vs. Missouri picks: See picks here
• Texas A&M vs. Missouri streaming: FuboTV (Try for free)

Why Texas A&M can cover

Texas A&M has bounced back nicely from its loss to Notre Dame, rattling off four consecutive wins. The Aggies have opened SEC play with two straight wins, beating Florida on the road and Arkansas in Arlington. Freshman quarterback Marcel Reed has stepped in as the starter the past three weeks, racking up 585 passing yards, six touchdowns and zero interceptions.

Junior running back Le’Veon Moss has 76 carries for 471 yards and three touchdowns, going over 100 yards in two of his last three games. Reed is a dual-threat quarterback who has rushed for 585 yards and six more scores. Missouri has not gone on the road yet this season, and this is an extremely challenging environment. See which team to pick here.

Why Missouri can cover

Texas A&M has taken advantage of four straight unranked opponents, but it had trouble slowing down Notre Dame in its only matchup against a top-25 team. The Aggies allowed 198 rushing yards in that game, and they are facing a Missouri rushing attack that ranks 26th nationally in rushing success rate. Senior running back Nate Noel has 441 rushing yards and two touchdowns, averaging 6.4 yards per carry.

Senior quarterback Brady Cook leads the balanced offense with 946 passing yards and four touchdowns, spreading the ball around to multiple receivers. Defensively, Missouri ranks fifth in success rate and 12th in passing success rate, so it will be difficult for Texas A&M to move the ball on Saturday. The Tigers have covered the spread in 11 of their last 15 games, including seven of their last eight road games. See which team to pick here. 

How to make Texas A&M vs. Missouri picks

The model has simulated Missouri vs. Texas A&M 10,000 times and the results are in. The model is leaning Over, and it’s also generated a point-spread pick that is hitting in well over 50% of simulations. You can only see the pick at SportsLine.

So who wins Texas A&M vs. Missouri, and which side of the spread is hitting well over 50% of the time? Visit SportsLine now to see which side of the Missouri vs. Texas A&M spread to jump on, all from the advanced computer model that’s up well over $2,000 on its top-rated college football spread picks since its inception, and find out.